医学
清创术(牙科)
炎症
伤口愈合
重症监护医学
殖民地化
慢性伤口
抗生素
缺血
外科
殖民地化
内科学
生物
微生物学
作者
Ruilong Zhao,Helena Liang,Elizabeth Clarke,Chris Jackson
摘要
Non-healing chronic wounds present a major biological, psychological, social, and financial burden on both individual patients and the broader health system. Pathologically extensive inflammation plays a major role in the disruption of the normal healing cascade. The causes of chronic wounds (venous, arterial, pressure, and diabetic ulcers) can be examined through a juxtaposition of normal healing and the rogue inflammatory response created by the common components within chronic wounds (ageing, hypoxia, ischaemia-reperfusion injury, and bacterial colonisation). Wound bed care through debridement, dressings, and antibiotics currently form the basic mode of treatment. Despite recent setbacks, pharmaceutical adjuncts form an interesting area of research.
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