The impacts of single irreversible reaction order on the combination style's efficiency of continuous-stirred tank reactor( CSTR) and plug flow reactor PFR were investigated. There were three kinds of combination style for two types of ideal flow reactors,i. e: one was CSTR followed by PFR,the second was PFR followed by CSTR,and the third was PFR and CSTR in parallel. The efficiency of different combination styles was evaluated with different reaction order for single irreversible reaction. When the reaction order was negative,the efficiency of PFR and CSTR in parallel was the highest among the three kinds of combination style. When the reaction order was in the range of 0 ~ 1,the efficiency of CSTR followed by PFR was the highest. When the reaction order was more than one,the efficiency of PFR followed by CSTR was the highest. When the reaction order was zero,three different kinds of combination style had the same efficiency. But when the reaction was first irreversible one,both CSTR followed by PFR and PFR followed by CSTR with the same efficiency,and higher than that of PFR and CSTR in parallel.