Analgesic effects of platelet‐rich fibrin (PRF): A systematic review

The autologous nature of PRF, along with the sustained release of bioactive factors, likely plays a vital role in modulating inflammation and promoting tissue healing, hence enhancing patient comfort and recovery. As PRF continues to gain traction in clinical practice, integrating well-designed comparative studies with standardized outcome measures will be necessary to completely understand its therapeutic potential and inform evidence-based guidelines regarding its application.