High Prevalence of Macrolide-resistant ptxP3-prn150 Bordetella pertussis in Jiangsu Province, China, 2024

The increasing prevalence of macrolide-resistant B. pertussis strains exhibiting ptxP3-prn150 genotype poses a significant challenge to both disease control and treatment. The high virulence associated with these strains, coupled with antibiotic resistance, underscores the urgent need for the development of novel vaccine strategies to effectively combat this emerging threat.