Screening the effective components of Lysionotus pauciflorus Maxim. on the treatment of LPS induced Acute lung injury mice by integrated UHPLC-Q-TOF-MS/MS and network pharmacology

Acute lung injury (ALI) is an inflammatory reaction produced through various injury-causing factors acting on the lungs in a direct or indirect way, with a high morbidity and mortality rate. A review of clinical experience has revealed that Lysionotus pauciflorus Maxim (LP) has a significant therapeutic effect on ALI. However, the comprehensive effective components of LP are uncertain, and the mechanisms, especially the potential therapeutic target for anti-ALI, are still unknown.