Kinesin-6 KIF20B is required for efficient cytokinetic furrowing and timely abscission in human cells

KIF20B is in the Kinesin-6 family that includes KIF23/MKLP1 and KIF20A/MKLP2. Previously we showed that mouse Kif20b regulates cerebral cortex growth and neural stem cell midbodies. Now we show KIF20B has a cell-autonomous role in regulating cytokinetic furrowing and abscission. KIF20B may coordinate late midbody maturation before abscission.