无色素性黑色素瘤
黑色素瘤
小眼畸形相关转录因子
黑色素
医学
皮肤病科
种系突变
生殖系
基因
生物
突变
癌症研究
遗传学
转录因子
作者
Maria Antonietta Pizzichetta,Harald Kittler,Ignazio Stanganelli,Giovanni Ghigliotti,Maria Teresa Corradin,Pietro Rubegni,S. Cavicchini,Vincenzo De Giorgi,R. Bono,Mauro Alaibac,Stefano Astorino,Fabrizio Ayala,Pietro Quaglino,Giovanni Pellacani,Giuseppe Argenziano,Davide Guardoli,Francesca Specchio,Diego Serraino,Renato Talamini
摘要
Amelanotic/hypomelanotic melanoma (AHM) is a subtype including melanomas with little or no melanin pigmentation, amelanotic melanoma (AM); it represents 2-8 % of all melanomas.1-2 AM may be difficult to diagnose because of lack of pigmentation and symmetry: recently, germline mutations have been reported in the MC1R gene and to a certain extent also in the MITF gene.3
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