苯妥英钠
杂合子丢失
胚胎
胎儿
畸形学
胚胎干细胞
生物
下调和上调
骨形态发生蛋白
内分泌学
内科学
怀孕
男科
遗传学
癫痫
基因
医学
神经科学
等位基因
作者
Jin‐Sil Park,Mitsushiro Nakatomi,Masaaki Sasaguri,Manabu Habu,Osamu Takahashi,Daigo Yoshiga,Kae Matsuyama,Shinji Kataoka,Takashi Toyono,Yuji Seta,Heiko Peters,Kazuhiro Tominaga
标识
DOI：10.1177/1055665620962690
摘要
Our data suggest that cleft palate may occur because of the additive effects of Bmp4 downregulation as a result of Msx1 heterozygosity and decreased cell proliferation upon hypoxic stress. Human carriers of MSX1 mutations may have to take more precautions during pregnancy to avoid exposure to environmental risks.
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(2025-6-4)
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