生物
新生隐球菌
鼠疫耶尔森菌
细胞内寄生虫
细胞内
微生物学
细菌
真菌
鼠疫(疾病)
病原真菌
收敛演化
毒力
基因
遗传学
系统发育学
植物
考古
历史
作者
James B. Bliska,Arturo Casadevall
摘要
The bacterium Yersinia pestis and the fungus Cryptococcus neoformans are the causative agents of human plague and cryptococcosis, respectively. Both microorganisms are facultatively intracellular pathogens. A comparison of their pathogenic strategies reveals similar tactics for intracellular survival in Y. pestis and C. neoformans despite their genetic unrelatedness. Both organisms can survive in environments where they are vulnerable to predation by amoeboid protozoal hosts. Here, we propose that the overall similarities in their pathogenic strategies are an example of convergent evolution that has solved the problem of intracellular survival.
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