Objective To analyze the reason of contrast media extravasation during enhanced CT in order to take prevention measures to avoid it in the daily examinations. Methods The patients who underwent contrast enhancement with high-pressure injector were divided into two groups of intravenous detaining needle and conventional scalp acupuncture. The extravasation states of contrast medium were observed for each case. Results The incidence of contrast medium exosmosis in intravenous detaining needle group was less than that of conventional scalp acupuncture group. Conclusion For enhanced CT examinations,the usage of intravenous detaining needle may effectively reduce extravasation of contrast medium and ensure the quality of CT imaging. Preventation is the most basic and important aspect to avoid extravasation.