Microarrays include cDNA microarray and oligonucleotide microarray. A lot of known partial sequences DNA probes were spotted on microarrays.Using principle of molecular hybridization,the compared samples (labelled with fluorescent or radioactivation)were hybridized parallelly with microarrays, then the intensity of hybridized signals were detected and transformed to proficiency of target genes by deta extraction system,the different gene expression of samples were compared in global. The technology is a efficient way to study genomic functions.