检出限
分子印迹聚合物
电化学气体传感器
二硫化钼
材料科学
分子印迹
印记(心理学)
纳米复合材料
离子液体
电化学
选择性
纳米技术
化学
色谱法
电极
生物化学
基因
物理化学
催化作用
冶金
作者
Axin Liang,Baoting Hou,Cong Tang,Duanping Sun,E. Aiqin Luo
标识
DOI:10.1016/j.bioelechem.2020.107671
摘要
An advanced molecularly imprinted electrochemical sensor with high sensitivity and selectivity for the detection of Human immunoglobulin G (IgG) was successfully constructed. With acrylamide imprinting systems, surface imprinting on the nanoparticles CuFe2O4 targeted at IgG was employed to prepare molecularly imprinted polymer, which served as recognition element for the electrochemical sensor. Furthermore, the sensor harnessed a molybdenum disulfide (MoS2)@nitrogen doped graphene quantum dots (N-GQDs) with ionic liquid (IL) nanocomposite for signal amplification. Under optimized experimental conditions, the sensor shortened the response time to less than 8 min, and the response was linear at the IgG concentration of 0.1–50 ng·mL−1 with a low detection limit of 0.02 ng·mL−1 (S/N = 3). Our findings suggested that, the sensor exhibited high detectability and long-time stability. The satisfactory results of human serum sample analysis showed that the developed IgG sensor had promising potential clinical applications in detecting IgG content.
科研通智能强力驱动
Strongly Powered by AbleSci AI