High-definition tDCS restores adaptable neural dynamics in migraine

Migraine is a common and disabling neurological disorder characterized by recurrent headaches and a spectrum of accompanying symptoms, including sensory hypersensitivities, cognitive impairment, nausea, and mood disturbances [1]. Increasing evidence suggests that migraine is associated with altered intrinsic brain activity, even outside of acute attacks (i.e., during the interictal phase). Neuroimaging studies have revealed substantial disruptions in spontaneous brain dynamics, including abnormal temporal variability [2], signal complexity [3], and oscillatory behavior [4].