Sulcatin, a Novel Antiproliferative N-Methylpyridinium Alkaloid from the Ascidian Microcosmus vulgaris

A new N-methylpyridinium alkaloid, with an interesting antiproliferative activity in vitro, has been isolated from the Mediterranean tunicate Microcosmus vulgaris. Its structure has been elucidated by spectroscopic analysis, including extensive 2D NMR experiments.