接受者
废止
分子内力
环丙烷
串联
组合化学
多米诺骨牌
立体化学
催化作用
作者
Matteo Faltracco,Matteo Damian,Eelco Ruijter
出处
期刊:Organic Letters
[American Chemical Society]
日期:2021-10-01
卷期号:23 (19): 7592-7596
被引量:1
标识
DOI:10.1021/acs.orglett.1c02795
摘要
An alkylation/olefination cascade of indolecarboxaldehydes and phosphonate-functionalized donor-acceptor cyclopropanes affords functionalized dihydrocarbazoles and cyclohepta[cd]indoles in formal (3 + 3) and (4 + 3) cycloadditions. A minor modification to the reaction conditions also allows access to the fully aromatic heterocyclic scaffolds by thermal loss of an electron-rich aryl moiety.
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