Molecular profile of glioblastoma

Glioblastoma multiforme (GBM) is one of the most devastating primary intracranial tumors in case of adults. The intricacy of GBM is contemplated at both the inter- and intra-tumoral levels by cellular and sub-molecular heterogeneity. Subsequently, various expected diagnostic, prognostic, and prescient biomarkers have been reflected. The current methodology and understanding of biomarkers of GBM are discussed here. We have also highlighted the molecular subtypes of GBM, genetic aberrations, and how the microRNAs are involved in glioblastoma.