Performance of a whole blood immunoassay for tenofovir detection and correlation with self‐reported pre‐exposure prophylaxis use in HIV‐negative men who have sex with men interested in blood donation

High concordance between self-reported oral PrEP use and TFV detection was observed among PrEP users, suggesting the potential utility of WB as a biomatrix for TFV detection to support screening strategies. Given the expanded eligibility for MSM, who may be PrEP users, to donate blood, further examination of undisclosed PrEP use is important.