Comparative Assessment of Compounds in Lawsonia Inermis L. - A Potent Antileishmanial Plant

Lawsonia Inermis L. plant, traditionally known as henna, played a svital role in the daily lives of ancient cultures, offering medicinal and psychological benefits, in addition to being used for personal beautification. The medicinal role of Lawsonia Inermis L. plant was known since ages and several isolated compounds from this plants plays an important role in the treatment of several tropical disease including Leishmaniasis. A large number of active compounds are present in this plant which could be used for the efficient treatment of this disease. Active compounds were collected from data bank of The Royal library/Copenhagen University library, PubMed, Scifinder, Reaxys, and Google Scholar etc. More than 161 compounds are identified, well-studied along with their molecular characterization from Lawsonia inermis L. plant out of which 20 compounds possess antileishmanial activity whereas 12 compounds were similar between Lawsonia inermis L and other plants that have Antileishmanial activities.. Although many studies reported the pharmacological activities of compounds isolated from Lawsonia Inermis L. plant in several diseases but the anti-leishmanial roles of compounds have not been widely investigated. The goal of present study was to evaluate the potential of the isolated compounds from Lawsonia Inermis L. plant in terms of their anti-leishmanial activity. The present review provides valuable information about compounds isolated from the Lawsonia Inermis L. plant, which could be considered in the future experimental and clinical trials for the treatment of leishmaniasis and other diseases.