FedMCC: Federated multi-center clustering algorithm to improve privacy healthcare

In recent years, healthcare data from various sources such as clinical institutions, patients, and pharmaceutical industries have become increasingly abundant. However, due to the complex healthcare system and data privacy concerns, aggregating and utilizing these data in a centralized manner can be challenging. Federated learning (FL) has emerged as a promising solution for distributed training in edge computing scenarios, utilizing on-device user data while reducing server costs. In traditional FL, a central server trains a global model sampled client data randomly, and the server combines the collected model from different clients into one global model. However, for not independent and identically distributed (non-i.i.d.) datasets, randomly selecting users to train server is not an optimal choice and can lead to poor model training performance. To address this limitation, we propose the Federated Multi-Center Clustering algorithm (FedMCC) to enhance the robustness and accuracy for all clients. FedMCC leverages the Model-Agnostic Meta-Learning (MAML) algorithm, focusing on training a robust base model during the initial training phase and better capturing features from different users. Subsequently, clustering methods are used to ensure that features among users within each cluster are similar, approximating an i.i.d. training process in each round, resulting in more effective training of the global model. We validate the effectiveness and generalizability of FedMCC through extensive experiments on public healthcare datasets. The results demonstrate that FedMCC achieves improved performance and accuracy for all clients while maintaining data privacy and security, showcasing its potential for various healthcare applications.