化学
羟胺
硝基苯
胺化
生物催化
有机化学
组合化学
催化作用
反应机理
作者
Shilong Gao,Anuvab Das,Edwin Alfonzo,Kathleen M. Sicinski,D. L. RIEGER,Frances H. Arnold
摘要
Hydroxylamine-derived reagents have enabled versatile nitrene transfer reactions for introducing nitrogen-containing functionalities in small-molecule catalysis, as well as biocatalysis. These reagents, however, result in a poor atom economy and stoichiometric organic waste. Activating hydroxylamine (NH
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