平衡
唾液
氧化应激
疾病
糖尿病
医学
病态的
生物信息学
免疫学
生物
病理
内分泌学
内科学
作者
Beáta Čižmárová,Vladimı́ra Tomečková,Beáta Hubková,Anna Hurajtová,Jana Ohlasová,Anna Birková
标识
DOI:10.3390/ijms231710076
摘要
Homeostasis is a self-regulatory dynamic process that maintains a stable internal environment in the human body. These regulations are essential for the optimal functioning of enzymes necessary for human health. Homeostasis elucidates disrupted mechanisms leading to the development of various pathological conditions caused by oxidative stress. In our work, we discuss redox homeostasis and salivary antioxidant activity during healthy periods and in periods of disease: dental carries, oral cavity cancer, periodontal diseases, cardiovascular diseases, diabetes mellitus, systemic sclerosis, and pancreatitis. The composition of saliva reflects dynamic changes in the organism, which makes it an excellent tool for determining clinically valuable biomarkers. The oral cavity and saliva may form the first line of defense against oxidative stress. Analysis of salivary antioxidants may be helpful as a diagnostic, prognostic, and therapeutic marker of not only oral, but also systemic health.
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