Self-made cationic agent WLS was applied in cationic modification of cotton fabric.the modified cotton fabric was salt-free dyed with reactive dyes.The optimal modification and dyeing technology of cationic agent WLS modified cotton fabric was determined.The dyeing behavior of modified cotton fabric was evaluated.The results showed that the modified fabric dyed with reactive dyes without salt addition had better K/S value and color fastness compared with those of the conventional salt dyed fabric.Cotton fabric modified with cationic agent WLS could be dyed with various reactive dyes without salt addition.