STUDIES OF ISOZYMES IN THE TISSUES OF RATTUS NIVIVENTER

By the method of isoelectro focusing PAGE,four kinds of isozymes in different tissues of Rattus niviventer captured in Beijing were studied.The dispersal and the activities of the isozyme bands were compared,and distinct organ specificity were found in EST isozymes,LDH isozymes and ADH isozymes,but not in SOD isozymes. The activities of isozymes were usually much higher in liver and kidney than in the other organs,but usually lower in spleen,lung and brain,except for EST isozymes in spleen and lung and except for LDH isozymes in brain.Heart muscle and skeleton muscle are significantly differential in LDH isozymes because of their difference in oxygen tension,nevertheless,they are quite similar in other three kinds of isozymes.The differences of various organs in isozymes are in keeping with their differences in physiological functions.