The clinical statistics for 385, patients, 300 males and 85 females, who underwent endolaryngeal microsurgery at the Department of Otorhinolaryngology at the Mie University Hospital between 1983 and 1992 are presented. Vocal fold polyps were seen most frequently, representing 127 cases (33.0%). Laryngeal cancers were found in 107 patients (27.8%), polypoid vocal folds in 43 (11.1%), and laryngeal cysts in 24 (6.2%). In 98 of the cases (25.5% of the total), the lesions were treated by application of a CO2 laser during endolaryngeal microsurgery. Of the various lesions laryngeal cancers were most frequently treated by CO2 laser. The incidence of complications with endolaryngeal microsurgery was 20.8% out of the total number of cases. Damage to the pharyngeal mucosa and/or oral mucosa, and numbness of the tongue were the major complications.