Progress of surfactin extraction and purification technologies

The progress of extraction and purification of surfactin is reviewed,including precipitation,solvent extraction,chromatographic purification,ultrafiltration,adsorption,foam fractionation and liquid film separation,with emphasis on selection and integrated application of these methods. In-situ product removal (ISPR),as one of integrated bioprocessing technologies,is an important research direction in industrial production of surfactin.