Mucosal immunity covers a variety of mucosal surfaces susceptible to different pathogens.This review explores the basic principles of mucosal immunity in light of the diversity of mucosal surfaces and their unique tissue environments,and offers some thoughts on approaches for developing vaccines to induce mucosal immunity,predominantly based on experiments studying immune responses to infection and vaccination in large animals.
Key words:
Mucous membrane; Immunity,mucosal; Vaccines