萧条(经济学)
医学
阿普加评分
荟萃分析
前瞻性队列研究
科克伦图书馆
产前抑郁症
产科
精神科
怀孕
儿科
内科学
胎儿
抑郁症状
焦虑
生物
遗传学
经济
宏观经济学
作者
Yifei Sun,Qing Chang,Qi‐Jun Wu,Shan‐Yan Gao,Si-Tian Zang,Yashu Liu,Yuhong Zhao
标识
DOI:10.1016/j.jad.2020.09.054
摘要
Antenatal depression is common, but most women with the condition choose to remain untreated. The Apgar score, an important indicator of newborn health, has been reported to be influenced by antenatal depression; thus, maternal antenatal depression, as reflected by a poor Apgar score, may harm children's health. To conduct a systematic review and meta-analysis to explore whether maternal antenatal depression is associated with the neonatal Apgar score. We registered the protocol for this study with PROSPERO (CRD42019137585). We searched PubMed, Embase, Web of Science, and the Cochrane Library for published papers that reported the association between depression and Apgar score from inception to December 4, 2019. Two reviewers independently screened and selected the studies according to the inclusion and exclusion criteria, and extracted data according to the predesigned table. Stata version 12.0 software was used to analyze data. We finally identified 13 studies for inclusion, including a total of 12017 women. We did not find an association between antenatal depression and the 1 min Apgar score of neonates (mean difference= -0.03, 95% CI= -0.15–0.09) or the risk of a low Apgar score (OR=1.82, 95% CI=0.51 to 3.13). We found that antenatal depression increased the risk of a low Apgar score at 5 min (OR= 1.91, 95% CI= 1.23–2.59), but the association between the 5 min Apgar score and antenatal depression was not significant (mean difference= -0.001, 95% CI= -0.07–0.07). The results of the subgroup analyses also indicated that there was no association between the 5 min Apgar score and antenatal depression. Antenatal depression increased the risk of a low 5 min Apgar score; however, we did not find a difference in the mean and distribution of neonatal Apgar scores of mothers with depression and mothers without depression.
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