表皮生长因子受体
肺癌
医学
奥西默替尼
药物开发
癌症研究
表皮生长因子受体抑制剂
第一代
埃罗替尼
酪氨酸激酶
药品
癌症
药理学
肿瘤科
内科学
受体
环境卫生
人口
作者
Die Zhang,Jumei Zhao,Yue Yang,Qiangfang Dai,Ning Zhang,Zhikuan Mi,Qianqian Hu,Xiaolong Liu
标识
DOI:10.1080/14756366.2025.2481392
摘要
, binding modes, pharmacokinetics, as well as the advantages and disadvantages of each inhibitor, alongside the progress of clinical stage research related to fourth-generation inhibitors. Additionally, the review discusses future development directions for fourth-generation EGFR-TKIs, aiming to provide insights for successful research and development in this field.
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