离体
肿瘤浸润淋巴细胞
CD40
流式细胞术
医学
免疫疗法
T细胞
肺癌
癌症研究
免疫系统
体内
免疫学
生物
肿瘤科
细胞毒性T细胞
体外
生物化学
生物技术
作者
R. A. M. Rossetti,Leticia Tordesillas,Matthew Beatty,Junior Cianne,Elena Martinez Planes,Dongliang Du,Sebastian Snedal,Chao Wang,Bradford A. Perez,Anders Berglund,Y. Ann Chen,Amod A. Sarnaik,James J. Mulé,Ben Creelan,Shari Pilon‐Thomas,Daniel Abate‐Daga
标识
DOI:10.1136/jitc-2024-011066
摘要
Our results show that CD40L-stimulated B-cells can be leveraged to enhance the quality and quantity of TIL. Clinical trial NCT05681780 is currently testing this concept applied to NSCLC TIL.
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