Is Elective Total Hip Arthroplasty Safe in Nonagenarians?

医学 队列 逻辑回归 人口 队列研究 外科 心力衰竭 糖尿病 内科学 环境卫生 内分泌学
作者
Vincent Justus Leopold,Paula Krull,Sebastian Hardt,Christian Hipfl,Oliver Melsheimer,Arnd Steinbrück,Carsten Perka,Gregor M. Giebel
出处
期刊:Journal of Bone and Joint Surgery, American Volume [Wolters Kluwer]
卷期号:105 (20): 1583-1593 被引量:1
标识
DOI:10.2106/jbjs.23.00092
摘要

An increasing number of elderly patients are becoming candidates for elective total hip arthroplasty (THA). Conflicting results exist with regard to the safety of THA in nonagenarians. The aims of this study were to evaluate postoperative mortality and morbidity after THA in nonagenarians and underlying risk factors. We hypothesized that nonagenarians undergoing elective THA would show higher morbidity than younger patients and higher mortality than nonagenarians in the general population.This was an observational cohort study using data from the German Arthroplasty Registry (Endoprothesenregister Deutschland [EPRD]). Of 323,129 THAs, 263,967 (including 1,859 performed on nonagenarians) were eligible. The mean follow-up (and standard deviation) was 1,070 ± 641 days (range, 0 to 3,060 days). The exclusion criteria were age of <60 years at admission and nonelective THAs or hemiarthroplasties. The cohort was divided into 4 age groups: (1) 60 to 69 years, (2) 70 to 79 years, (3) 80 to 89 years, and (4) ≥90 years. Comorbidities representing independent risk factors for postoperative complications and mortality were identified via a logistic regression model. Mortality rates were compared with those from the general population with data from the Federal Statistical Office. The end points of interest were postoperative major complications, minor complications, and mortality.Among the greatest risk factors for major and minor complications and mortality were congestive heart failure, pulmonary circulation disorders, insulin-dependent diabetes, renal failure, coagulopathy, and fluid and electrolyte disorders. Compared with younger groups, the risks of major and minor complications and mortality were significantly higher in nonagenarians. Mortality increased when major complications occurred. After 1 year, the survival rate in patients without a major complication was 94.4% compared with 79.8% in patients with a major complication. The mortality rates of nonagenarians in the study population were lower than those in the corresponding age group of the general population. The 1-year mortality rates at 90 years of age were 10.5% for men and 6.4% for women within the study group compared with 18.5% for men and 14.7% for women among the general population.Comorbidities favor the occurrence of complications after elective THA in nonagenarians and thus increase postoperative morbidity. In the case of complications, mortality is also increased. The fact that mortality is still lower than within the general population shows that this aspect can be controlled by careful patient selection and adequate preparation.Therapeutic Level III . See Instructions for Authors for a complete description of levels of evidence.

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
arisfield完成签到,获得积分10
刚刚
7秒前
科研通AI2S应助科研通管家采纳,获得10
7秒前
科研通AI5应助科研通管家采纳,获得10
7秒前
星辰大海应助科研通管家采纳,获得10
8秒前
典雅问寒应助科研通管家采纳,获得10
8秒前
典雅问寒应助科研通管家采纳,获得10
8秒前
8秒前
wonder123应助科研通管家采纳,获得10
8秒前
科研通AI5应助科研通管家采纳,获得10
8秒前
科研通AI5应助科研通管家采纳,获得10
8秒前
9秒前
GYJ完成签到 ,获得积分10
12秒前
Robin发布了新的文献求助10
13秒前
00完成签到 ,获得积分10
15秒前
17秒前
17秒前
ss应助无心的土豆采纳,获得10
20秒前
哎呦哎完成签到,获得积分10
22秒前
www发布了新的文献求助10
22秒前
25秒前
SCI的芷蝶发布了新的文献求助10
28秒前
略略略完成签到 ,获得积分10
28秒前
muhum完成签到 ,获得积分10
30秒前
www完成签到,获得积分10
32秒前
33秒前
33秒前
小艾完成签到,获得积分10
35秒前
38秒前
欧凰发布了新的文献求助30
39秒前
Robin发布了新的文献求助10
40秒前
41秒前
42秒前
MAKEYF完成签到 ,获得积分10
44秒前
吴晓敏关注了科研通微信公众号
45秒前
yuaner发布了新的文献求助10
45秒前
45秒前
白鸽鸽完成签到,获得积分10
49秒前
50秒前
yuaner完成签到,获得积分10
51秒前
高分求助中
【此为提示信息,请勿应助】请按要求发布求助,避免被关 20000
Continuum Thermodynamics and Material Modelling 2000
Encyclopedia of Geology (2nd Edition) 2000
105th Edition CRC Handbook of Chemistry and Physics 1600
Maneuvering of a Damaged Navy Combatant 650
Периодизация спортивной тренировки. Общая теория и её практическое применение 310
Mixing the elements of mass customisation 300
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 物理 生物化学 纳米技术 计算机科学 化学工程 内科学 复合材料 物理化学 电极 遗传学 量子力学 基因 冶金 催化作用
热门帖子
关注 科研通微信公众号,转发送积分 3778761
求助须知:如何正确求助?哪些是违规求助? 3324341
关于积分的说明 10217907
捐赠科研通 3039436
什么是DOI,文献DOI怎么找? 1668081
邀请新用户注册赠送积分活动 798544
科研通“疑难数据库(出版商)”最低求助积分说明 758415