Is Elective Total Hip Arthroplasty Safe in Nonagenarians?

医学 队列 逻辑回归 人口 队列研究 外科 心力衰竭 糖尿病 内科学 环境卫生 内分泌学
作者
Vincent Justus Leopold,Paula Krull,Sebastian Hardt,Christian Hipfl,Oliver Melsheimer,Arnd Steinbrück,Carsten Perka,Gregor M. Giebel
出处
期刊:Journal of Bone and Joint Surgery, American Volume [Wolters Kluwer]
卷期号:105 (20): 1583-1593 被引量:1
标识
DOI:10.2106/jbjs.23.00092
摘要

An increasing number of elderly patients are becoming candidates for elective total hip arthroplasty (THA). Conflicting results exist with regard to the safety of THA in nonagenarians. The aims of this study were to evaluate postoperative mortality and morbidity after THA in nonagenarians and underlying risk factors. We hypothesized that nonagenarians undergoing elective THA would show higher morbidity than younger patients and higher mortality than nonagenarians in the general population.This was an observational cohort study using data from the German Arthroplasty Registry (Endoprothesenregister Deutschland [EPRD]). Of 323,129 THAs, 263,967 (including 1,859 performed on nonagenarians) were eligible. The mean follow-up (and standard deviation) was 1,070 ± 641 days (range, 0 to 3,060 days). The exclusion criteria were age of <60 years at admission and nonelective THAs or hemiarthroplasties. The cohort was divided into 4 age groups: (1) 60 to 69 years, (2) 70 to 79 years, (3) 80 to 89 years, and (4) ≥90 years. Comorbidities representing independent risk factors for postoperative complications and mortality were identified via a logistic regression model. Mortality rates were compared with those from the general population with data from the Federal Statistical Office. The end points of interest were postoperative major complications, minor complications, and mortality.Among the greatest risk factors for major and minor complications and mortality were congestive heart failure, pulmonary circulation disorders, insulin-dependent diabetes, renal failure, coagulopathy, and fluid and electrolyte disorders. Compared with younger groups, the risks of major and minor complications and mortality were significantly higher in nonagenarians. Mortality increased when major complications occurred. After 1 year, the survival rate in patients without a major complication was 94.4% compared with 79.8% in patients with a major complication. The mortality rates of nonagenarians in the study population were lower than those in the corresponding age group of the general population. The 1-year mortality rates at 90 years of age were 10.5% for men and 6.4% for women within the study group compared with 18.5% for men and 14.7% for women among the general population.Comorbidities favor the occurrence of complications after elective THA in nonagenarians and thus increase postoperative morbidity. In the case of complications, mortality is also increased. The fact that mortality is still lower than within the general population shows that this aspect can be controlled by careful patient selection and adequate preparation.Therapeutic Level III . See Instructions for Authors for a complete description of levels of evidence.

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
Ava应助科研通管家采纳,获得10
刚刚
打打应助科研通管家采纳,获得10
刚刚
李健应助科研通管家采纳,获得10
刚刚
刚刚
健忘丹珍完成签到,获得积分10
刚刚
烟花应助科研通管家采纳,获得10
刚刚
刚刚
CodeCraft应助科研通管家采纳,获得10
刚刚
Akim应助科研通管家采纳,获得10
刚刚
张晓芳完成签到,获得积分10
刚刚
桐桐应助fangsci采纳,获得10
1秒前
情怀应助科研通管家采纳,获得10
1秒前
1秒前
1秒前
科目三应助科研通管家采纳,获得10
1秒前
赘婿应助科研通管家采纳,获得10
1秒前
华仔应助科研通管家采纳,获得10
1秒前
CodeCraft应助科研通管家采纳,获得10
1秒前
王王应助科研通管家采纳,获得30
1秒前
ohnono完成签到,获得积分10
1秒前
2秒前
佟鹭其完成签到 ,获得积分10
3秒前
赶紧毕业完成签到,获得积分10
4秒前
吴灵完成签到,获得积分10
4秒前
流沙无言发布了新的文献求助10
4秒前
脑残骑士老张完成签到,获得积分10
4秒前
5秒前
和谐诗双完成签到 ,获得积分10
6秒前
zyy完成签到 ,获得积分10
7秒前
快乐慕灵完成签到,获得积分10
7秒前
meimale完成签到,获得积分10
8秒前
复杂的傲松完成签到,获得积分10
8秒前
11完成签到 ,获得积分10
8秒前
dapan0622完成签到,获得积分10
8秒前
儒雅的焦完成签到 ,获得积分10
8秒前
芹菜完成签到,获得积分10
8秒前
聪明的豆沙卷完成签到,获得积分10
9秒前
积极的依白完成签到 ,获得积分10
9秒前
中午吃什么完成签到,获得积分10
9秒前
甜甜完成签到,获得积分10
9秒前
高分求助中
(应助此贴封号)【重要!!请各用户(尤其是新用户)详细阅读】【科研通的精品贴汇总】 10000
Lewis’s Child and Adolescent Psychiatry: A Comprehensive Textbook Sixth Edition 2000
Cronologia da história de Macau 1600
Continuing Syntax 1000
Encyclopedia of Quaternary Science Reference Work • Third edition • 2025 800
Influence of graphite content on the tribological behavior of copper matrix composites 658
Interaction between asthma and overweight/obesity on cancer results from the National Health and Nutrition Examination Survey 2005‐2018 600
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 纳米技术 计算机科学 化学工程 生物化学 物理 复合材料 内科学 催化作用 物理化学 光电子学 细胞生物学 基因 电极 遗传学
热门帖子
关注 科研通微信公众号,转发送积分 6211520
求助须知:如何正确求助?哪些是违规求助? 8037832
关于积分的说明 16745295
捐赠科研通 5300532
什么是DOI,文献DOI怎么找? 2824194
邀请新用户注册赠送积分活动 1802709
关于科研通互助平台的介绍 1663781