微粒
药物输送
纳米技术
纳米-
化学
靶向给药
细胞
材料科学
化学工程
生物化学
工程类
复合材料
作者
Maxime Ayer,Harm‐Anton Klok
标识
DOI:10.1016/j.jconrel.2017.01.048
摘要
Cell mediated delivery of synthetic nano- and microparticle based drug carriers is a very promising strategy to enhance control over the distribution of drugs and improve targeting. This article will present an overview of work, which has been done to explore cell surface modification strategies for the cellular hitchhiking of synthetic nano- and microparticles. The first part of this article will present and discuss the different types of cells that have been explored for cell mediated drug delivery. The second part of this review will discuss the various chemical strategies that have been elaborated for the conjugation or immobilization of nano- and microparticles on the surface of these cells.
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