Clinic cases of application of aminophylline.

Objective To monitor the blood concentration of aminophylline in order to use it reasonably.Methods According to the ADR reports of aminophylline,the relation of blood concentration and therapeutic effect of aminophylline were analyzed.Results Blood concentration of 9 patients using aminophylline combined with Quinolone antibacterial or H2 receptor blockers,anti-arrhythmic drugs was higher than 20 μg/mL(effective concentration),then the ADR occured.Conclusion Blood concentration of aminophylline should be monitored when clinic using.The individual medication should be guaranteed according to patients′ physiology,pathology,pharmaco-toxicology,interaction and therapeutic effect.