Aim To explore the correlation between thrombosis and density change of gores.Methods Using physic methods in new blood samples,the natural thrombus is taken and used the blood boltsof differentages(gores,flowing out of our bodies in different intervals) is used to calculate the changes of density parameters in the gores.Results During the process of thrombosis,the density of thrombus was increasing obviously along with the gore forming time.That made it positive relationship that density of the clot complied with the prolonging thrombus ageing.It reflected that all the state changes during thrombosis had distinct changes of physical parameters.Conclusion The results showed that thrombus density has the characteristics of the changing with the gore aging.This may also provide reliable evidence that the changes of thrombus structures and densities may improve the effect of intravascular ultrasonic thrombosis ablation and may be beneficial of clinic use.