Studies of Soy Isoflavones on Antioxidation

Objective: To investigate the antioxidation effects of soy isoflavones in mice during an experimental period of 8 weeks. Methods: 60 BALB/C male mice (18～22g , BW) were divided randomly into 4 groups and fed a basal diet supplemented with 25,100, 200mg/kg soy isoflavones. Results:The MDA and H2O2 levels in liver were significantly lower than those of the control group (p0.01). The GSH-Px and CAT activities of in liver and whole blood were increased obviously (p0.01). The SOD, T-AOC levels in liver were significantly increased (p0.01). Conclusion: These results suggested that soy isoflavones can improve the ability of antioxidation obviously.