可药性
药物发现
药品
背景(考古学)
药物作用
系统药理学
生物网络
药理学
计算生物学
机制(生物学)
动作(物理)
生物
生物信息学
遗传学
基因
认识论
物理
哲学
古生物学
量子力学
出处
期刊:PubMed
日期:2011-08-01
卷期号:42 (4): 241-5
被引量:6
摘要
The pharmaceutical industry has historically relied on particular families of 'druggable' proteins against which to develop compounds with desired actions. But proteins rarely function in isolation in and outside the cell; rather, proteins operate as part of highly interconnected cellular networks. Network pharmacology is an emerging area of pharmacology which utilizes network analysis of drug action. By considering drug actions in the context of the cellular networks, network analysis promises to greatly increase our knowledge of the mechanisms underlying the multiple actions of drugs. Network pharmacology can provide new approaches for drug discovery for complex diseases. This review introduced the recent progress of network pharmacology and its importance to understand the mechanism of drug actions and drug discovery.
科研通智能强力驱动
Strongly Powered by AbleSci AI