Synthesis, Characterization and Antimicrobial Activity of Copper-Metal Organic Framework (Cu-MOF) and Its Modification by Melamine

Copper-Metal organic framework (Cu-MOF) and melamine/Cu-MOF (MCu-MOF) samples were prepared by the hydrothermal process. The produced powder was dried and characterized by using the FTIR, X-ray techniques. The thermal-gravimetry (TG) analysis was performed to detect the thermal stability of the product. On other hand, the morphology and the surface area of this powder were carried. The bioactivity of the powder was carried by measuring the inhibition zone diameter around samples in (mm). The results of characterization showed that on the IR spectra a series of absorption peaks at 970, 1500 and 1640 cm−1 were appeared which characterized the formation of Cu-MOF, while an addition peaks were observed at 3121, 3324, 3415 and 3467 cm−1 and attributed to the incorporation of melamine into Cu-MOF. X-ray patterns of the prepared samples show sharp peaks at 7.4 and 8.5 specified to Cu-MOF. The intensity of these peaks increases by adding melamine which indicate the improving the crystanility. Moreover two peaks at 26, 30attributed to the incorporate melamine in the Cu-MOF. The surface area of Cu-MOF is equal to 1350 m2 g−1while increase to 1410 m2 g−1 by incorporates melamine into the Cu-MOF. The thermal behavior (TG) of the Cu-MOF showed three sequence stages attributed to the moisture evaporation, degradation of the Cu-MOF and forming the Cu–O as end product respectively. For melamine incorporated to Cu-MOF (MCu-MOF), the TG profile split the main degradation into two parts resulting from the presence of melamine. To study the morphology of these samples by both FESEM and HRTEM were examined. The bioactivities of the both samples were tested against microbial strains. The results showed that the Cu-MOF and MCu-MOF have insignificant antimicrobial activity against gram positive of bacteria and Fungi. While for gram negative of bacteria it is observed a considerable effect.