Accelerated Surgery Versus Standard Care in Hip Fracture (HIP ATTACK-1): A Kidney Substudy of a Randomized Clinical Trial

Acute kidney injury (AKI) is a lesser-known complication of hip fracture that may come about owing to decreased kidney perfusion and heightened inflammation from trauma, pain, bleeding, and fasting.1,2 Approximately 15%-20% of patients undergoing surgery for a hip fracture develop AKI, with 0.5%-1.8% receiving dialysis.3-5 A strategy of accelerating the time to surgery after a hip fracture was recently compared with standard care in HIP ATTACK-1 (ClinicalTrials.gov identifier NCT02027896), a multinational randomized clinical trial.