Abstract Role of soil to meet global food security, sustainable intensification and food nutritional quality has got renewed attention with a larger focus on soil physical condition. No-tillage (NT) practice can essentially contribute to develop a sustainable, low carbon and resource efficient agriculture, and encourage the use of crop residues for added soil benefits. Soil aggregation and pore size distribution, two most important soil physical factors controlling the mass and energy transport processes within the soil and between soil and environment, were evaluated under the NT through a global meta-analysis of 5065 pairs of data points from 419 peer-reviewed studies. Compared to conventional tillage (CT), NT increased mean weight diameter of aggregates, water stable aggregates, and macroaggregates by averages (0–30 cm) of 25, 10 and 22%, respectively, although predominantly in 0–10 and/or 10–20 cm layers, with an accompanying reduction in microaggregates. A small but significant 3% decrease in total porosity, a large reduction (20–32%) in macroporosity and a moderate increase (4–7%) in microporosity were realized under NT up to 20 cm soil depth. Bulk density remained stable, although a very large decrease (70% change over CT) in saturated hydraulic conductivity was recorded in 10–20 and >30 cm soil layers. Years of adoption of NT had an additive effect on mean weight diameter and macroaggregates, and the total and macroporosity. Increase in latitudes favoured soil aggregation and micropore volume under NT, while clay content was unfavourable to macro- and water stable aggregate contents. Improvement in structure and water retention properties relate to long-term sustainable development of soils by following no-till practice, which has far-reaching implications beyond the boundaries of agronomy.