医学
羊水过少
缬沙坦
怀孕
妊娠期
儿科
肾病科
肾脏疾病
子宫内
产科
内科学
作者
Sarah Petch,Emily O'Connor,Ailbhe McGrath,Sean Daly
出处
期刊:Case Reports
[BMJ]
日期:2021-05-19
卷期号:14 (5): e240810-e240810
被引量:1
标识
DOI:10.1136/bcr-2020-240810
摘要
In utero exposure to angiotensin II receptor blockers (ARBs) has fetotoxic effects including renal failure, oligohydramnios and lung hypoplasia. We present the case of a 24-year-old woman who presented to the maternity services in the 34th week of her first pregnancy. She was taking valsartan for hypertension. Ultrasound showed a structurally normal fetus with anhydramnios. The patient was admitted and valsartan was discontinued. She had spontaneous preterm delivery at 35 weeks’ gestation of a baby girl. The baby’s urine output was minimal in the first week of life and she was transferred to a paediatric hospital for specialist nephrology input. At 6 months of age, she requires ongoing nephrology follow-up and she remains on treatment for hypertension and anaemia. This case demonstrates the serious adverse effects resulting from ARB exposure in utero, and highlights the importance of avoiding fetotoxic medications in women of childbearing age.
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