Visible‐Light‐Driven Three‐Component β‐CF 2 ‐Pyridylation of Styrenes via EDA Complex Formation

A visible‐light‐induced, catalyst‐free three‐component difluoroalkylpyridylation of styrenes is reported. This transformation proceeds via an electron donor–acceptor (EDA) complex formed between bromodifluoroacetate and Hantzsch ester (HE), enabling efficient access to β‐CF 2 ‐pyridylated arenes under mild conditions. Mechanistic studies support a radical pathway involving EDA‐mediated CBr bond cleavage and subsequent radical coupling. This method offers a sustainable strategy for incorporating both difluoromethylene and pyridine motifs into styrenes.