Origin of Chemo-and Stereoselectivity in NHC-Catalyzed Asymmetric Intermolecular Cycloadditions of Hydrazone and Isatin

Due to the multiple active sites of hydrazine, the origin of chemo-and stereoselectivity for N-heterocyclic carbene (NHC)catalyzed cycloadditions of hydrazone remains unclear. This theoretical study employs density functional theory (DFT)...