中性粒细胞胞外陷阱
细胞生物学
效应器
化学
细胞外
存水弯(水管)
肺
炎症
细胞内
信号转导
趋化性
生物物理学
下调和上调
细胞
粒细胞
细胞信号
发病机制
中性粒细胞
生物
作者
Shuhua Luo,Qianqian Zhang,Wending Zhou,Lina Zhang,Chaoxiong Liao,Dan Zeng,Liangqing Zhang,Fu-li Xiang,Jie Xu,Jing Tang
标识
DOI:10.1016/j.jare.2026.01.044
摘要
Collectively, our findings uncover a novel METTL3-SYK epitranscriptomic axis that governs neutrophil effector responses during endotoxin-induced lung injury. These results highlight m6A-dependent post-transcriptional regulation as a potential therapeutic target in ALI and sepsis-associated inflammation.
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