Acute Retinal Necrosis Associated Rhegmatogenous Retinal Detachment: A Systematic Review and Meta-Analysis

PURPOSE: To evaluate the success of surgical management for rhegmatogenous retinal detachment (RRD) secondary to acute retinal necrosis (ARN). METHODS: PubMed, Embase, ClinicalTrials, the Cochrane Library, and grey literature (2000-present) were searched for case series, interventional, and cohort studies reporting surgical repair of ARN-related RRD. Interventions included pars plana vitrectomy (PPV), scleral buckle (SB), and tamponade agents. Outcomes were final anatomical reattachment, visual acuity (VA), complications, and re-detachment. Study quality was assessed using the Newcastle-Ottawa Scale. A single-arm random-effects meta-analysis with subgroup analysis by surgical technique was performed using R. RESULTS: = 0.026). CONCLUSION: Surgical repair of ARN-related RRD yields high anatomical success, but visual recovery remains limited and technique-dependent. Combined PPV + SB provides the most favorable structural and functional outcomes without increased complication risk, supporting its preferential use.