ELEVATED PLASMA TRIMETHYLAMINE-N-OXIDE IS ASSOCIATED WITH POOR PROGNOSIS IN PATIENTS WITH PERIPHERAL ARTERY DISEASE

Production of trimethylamine-N-oxide (TMAO) by gut-microbiota metabolite from dietary phosphatidylcholine has been associated with the development of atherosclerosis in animals and in humans. The ability of plasma TMAO to predict future risk of major adverse cardiac events (MACE=death, myocardial