Objective To analyze the effect of clinical factors on implant osseointegration formation. Methods A clinical study using the Branemark dental implant system was carried out on 230 patients. The second stage procedure was performed at 3-6 months postoperatively. The status of implant osseointegration was assessed by X-ray and clinical examination. Result Among 520 dental implants inserted,503 dental implants acquired osseointegration, 17 implants failed to osseointegrate and the success rate was 96.7%. Conclusion The dental implant osseointegration formation depends on selecting indication,presurgical preparing, subtle surgical manipulation, and preventing bone burning, inflammation of operation aera and contamination of dental implants.