Cardiorenal syndrome in patients with chronic heart failure

Aim. The relevance of the chosen research direction is stipulated by increasing prevalence of chronic cardiovascular disease and states associated with it.Methods and results. In order to evaluate the filtration function of the kidneys in patients with CHF there were examined 40 male patients with a verified disorder of left ventricular systolic function, occurred at a background of coronary heart disease and hypertension and 30 healthy individuals of the same age with determination of glomerular filtration rate (GFR) by endogenous creatinine clearance. It is shown that in patients with impaired left ventricular systolic function in the background of coronary heart disease and hypertension the chronic kidney disease is manifested. The concentration of creatinine in patients ranged reference values 85,2 ±0,4 mmol / l, and the glomerular filtration rate is closely correlated (r=0,60) with the degree of violation of left ventricular systolic function. Conclusion. This indicates the formation of cardiorenal syndrome encumbrance and mutual pathologies of the cardiovascular system and chronic kidney disease.