The clinical efficacy of “water-jet” hemostasis in gastrointestinal endoscopic submucosal dissection

Abstract Objective This study aims to evaluate the safety and efficacy of “water-jet” hemostasis during endoscopic submucosal dissection. Methods In this prospective single-arm clinical study, 10 patients aged 18–60 years with gastric or intestinal mucosal lesions who were admitted to Fujian Medical University Xiamen Humanity Hospital (Xiamen, P. R. China) between June 2022 and June 2023 and met the absolute indications for endoscopic treatment were finally analyzed. The primary outcomes of this study are the incidence rates of adverse events and R0 resection, and the secondary outcomes are length of hospital stay and short- and long-term outcomes. Results Successful hemostasis was achieved in all the included cases. In one case, the “water-jet” hemostasis failed to stop bleeding in one blood vessel, so the hemostatic forceps were used instead. No adverse events occurred in all cases. Pathologic results showed R0 resection in all samples. Conclusion The “water-jet” method is safe and feasible for hemostasis in endoscopic submucosal dissection.