曲唑酮
CYP2D6型
药代动力学
药理学
药物遗传学
CYP1A2
医学
细胞色素P450
基因型
内科学
抗抑郁药
生物
遗传学
新陈代谢
基因
海马体
作者
Jessica Meulman,Marília Berlofa Visacri,Patrícia Moriel,Eder de Carvalho Pincinato
标识
DOI：10.1097/ftd.0000000000001049
摘要
Polymorphisms in CYP450 do not seem to directly influence the pharmacokinetics of trazodone hydrochloride or its metabolites. By contrast, genetic polymorphisms in ABCB1 seem to have an important effect on the pharmacokinetics of trazodone hydrochloride by enhancing drug metabolism and elimination.
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(2025-6-4)
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