Transforming “cold” tumors into “hot” ones via immunogenic cell death by Bufadienolides for reverses immunosuppressive TME in HCC

Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related death worldwide. Unfortunately, the inherently immunosuppressive tumor microenvironment (TME) severely limited the anti-tumor efficacy of conventional therapies. Immunogenic...