荧光
检出限
铜
选择性
猝灭(荧光)
金属有机骨架
化学
金属
加合物
信号(编程语言)
螯合作用
光化学
分析化学(期刊)
无机化学
物理化学
色谱法
有机化学
催化作用
吸附
计算机科学
程序设计语言
物理
量子力学
作者
Ya-Nan Zuo,Shuyi Liu,Xian‐En Zhao,Shuyun Zhu,Guobao Xu
标识
DOI:10.1016/j.snb.2023.134487
摘要
As the main existing form of copper, Cu+ plays vital roles in human health. It is highly significant to detect Cu+ selectively in biological matrixes especially in the coexistence of Cu2+. Herein, a ratiometric fluorescence sensor has been fabricated to discriminate Cu+ from Cu2+ and realize ratiometric detection of Cu+ by using Tb-MOFs and bathocuproine disulfonate (BCS). The sensor exhibits two fluorescence emissions at 400 nm from BCS as the response signal and 548 nm from Tb-MOFs as the reference signal. BCS can chelate with Cu+ selectively to form a stable adduct, inducing the fluorescence quenching of BCS through static quenching. When Cu+ is added, the intensity at 400 nm decreases significantly while that at 548 nm changes negligibly. Notably, the presence of Cu2+ exhibits no effect on the emissions both at 400 nm and 548 nm. Thus, Tb-MOFs-BCS system enable discrimination of Cu+ from Cu2+ and fast ratiometric detection of Cu+ within 1 min. The fluorescence ratio (F548/F400) shows a good linear relationship in Cu+ concentrations ranging from 1 nM to 200 nM with a low detection limit of 0.3 nM, which is 1–3 orders magnitude lower than those of other methods. The high selectivity and sensitivity of this method enables the detection of Cu+ in human serum successfully.
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